Agenda

Your Subtitle text

Agenda

The primary focus of this conference will be in the following disciplines:

Basic Research—new findings in molecular, immunological, and pathogenesis and epidemiologic research, vaccine delivery and adjuvants.

Applied Research—vaccine products; assay development; biomarkers; and preclinical studies.

Clinical Studies on TB Vaccines—vaccines in clinical studies; lessons learned from trials; immunization strategies; phase II and III studies; next generation vaccines.

Manufacturing, Regulation and Vaccine Access— pilot facilities; industrial development of TB vaccines; role of developing countries; IP issues and technology transfer; global regulation pathways; GMP assays.

Partnerships, Communication & Coordination—role of major institutions and international organizations in TB vaccine development; coordinating new vaccine and new diagnostics studies; working in developing countries.

Schedule At-a-Glance
To download a printable version of the schedule, please click here.

Tuesday, September 21
02:00 - 08:00 PM	Registration
12:00 - 03:00 PM	Complimentary walking tours (departing at 12:00 PM, 1:00 PM & 2:00 PM)
04:00 – 05:30 PM	Special Opening Session How Tuberculosis Influenced History Timo Ulrichs, Koch-Mechnikov Forum Current Status of TB in the World Chris Dye, World Health Organization TB in the Eastern European Region: A community perspective Julia Kashina, Estonian Network of People Living with HIV The Role of TB Vaccines in Addressing the Global Epidemic Peter Small, Bill & Melinda Gates Foundation
06:00 - 08:00 PM	Welcome Reception The Honorable Hanno Pevkur, Estonian Minister of Social Affairs
Wednesday, September 22
08:00 - 08:30 AM	Registration
08:30 - 08:45 AM	Welcome Introduction Michael Brennan, Aeras Global TB Vaccine Foundation Ulrich Fruth, World Health Organization
08:50 - 09:00 AM	Stop TB Task Force Presentation Overview of the Working Group on New TB Vaccines Michel Gréco, Stop TB Partnership Working Group on New TB Vaccines
09:00 - 11:30 AM	Session I: Basic Research Co-Chairs: Paul-Henri Lambert, University of Geneva William Jacobs Jr., Albert Einstein College of Medicine
09:00 - 09:30 AM	Latent TB and the Next Generation of Vaccines Peter Andersen, Statens Serum Institute
09:30 - 10:00 AM	Reconstruction and comparative analysis of the TB regulatory network James Galagan, Boston University
10:00 - 10:30 AM	Coffee/Tea Break
10:30 - 11:00 AM	Tuberculosis Vaccine Research at the Interface Between Vaccinology and Immunology. Stefan H.E. Kaufmann, Max Planck Institute for Infection Biology
11:00 - 11:30 AM	Session I Q&A/Panel Discussion Special Topic: The role of Fundamental Research in Global TB Control Christian Lienhardt, Stop TB Partnership
11:30 - 2:40 PM	Session II: Applied Research Co-Chairs: Alexander Apt, Central Institute for TB Hazel Dockrell, London School of Hygiene & Tropical Medicine
11:30 – 11:40 PM	Stop TB Task Force Presentation Immunoassays in TB Vaccine Development Hazel Dockrell, London School of Hygiene & Tropical Medicine
11:40 - 12:10 PM	The Challenge of Correlates of Immunity Jerrold Ellner, Boston Medical College
12:10 - 01:10 PM	Lunch
01:10 - 01:40 PM	Diverse T Cell Activation of New Vaccines and Correlates of Protection Willem Hanekom, South African Tuberculosis Vaccine Initiative
01:40 - 02:10 PM	Development of a New Attenuated Vaccine: from Preclinical to Clinical Evaluation Carlos Martin, Universidad de Zarazoga William Jacobs, Jr., Albert Einstein College of Medicine
02:10 - 02:40 PM	Session II Q&A/Panel Discussion Special Topic: Current Breakthroughs in Immunology Tom Ottenhoff, Leiden University Medical Center David Lewinsohn, Oregon Health & Science University
02:40 - 05:10 PM	Session III: Manufacturing, Regulation and Vaccine Access Co-Chairs: Pascal Mettens, GlaxoSmithKline Biologicals Sheldon Morris, U.S. Food and Drug Administration
02:40 - 02:50 PM	Stop TB Task Force Presentation Economic Issues in TB Vaccine Development Gerard Cunningham, The Bill & Melinda Gates Foundation
02:50 - 03:20 PM	Vaccine access to China: Opportunities and Challenges Daniel Chin, The Bill & Melinda Gates Foundation
03:20 - 03:40 PM	Coffee/Tea Break
03:40 - 04:10 PM	Manufacturing using HBHA Camille Locht, Inserm/ Institut Pasteur de Lille
04:10 - 04:40 PM	Title to be determined Speaker to be determined
04:40 - 05:10 PM	Session III Q&A/Panel Discussion Report of Study on Barriers and Drivers for Introduction of New TB Vaccines Lew Barker, Aeras Global TB Vaccine Foundation
05:10 - 06:30 PM	Poster Viewing
07:00 - 09:30 PM	Conference Dinner Keynote Presentation: “The Decades of TB Vaccines: Looking Back and Looking Forward” Peter Small, The Bill & Melinda Gates Foundation
09:30 - 11:00 PM	Poster Viewing (Continued)
Thursday, September 23
08:30 - 12:00 PM	Session IV: Clinical Studies on TB Vaccines Co-Chairs: Harriet Mayanja-Kizza, Kampala University Greg Hussey, University of Cape Town
08:30 - 08:40 AM	Stop TB Task Force Presentation Clinical Research Issues in TB Vaccine Development Hassan Mahomed, South African Tuberculosis Vaccine Initiative
08:40 - 08:50 AM	Clinical Trial Challenges Thomas G. Evans, MD, Aeras Global TB Vaccine Foundation
08:50 - 09:50 AM	TB Vaccines in Clinical Trials:
	MVA85A Helen McShane, Oxford University
	AERAS-402/Crucell Ad35 Jerald Sadoff, Crucell
	SSI Vaccines Søren Hoff, Statens Serum Institut
	M72 Opokua Ofori-Anyinam, GlaxoSmithKline Biologicals
09:50 - 10:10 AM	Q & A for Speakers
10:10 - 10:30 AM	Coffee/Tea Break
10:30 - 11:30 AM	TB Vaccines in Clinical Trials (con’t):
	VPM1002 Leander Grode, Vakzine Projekt Management
	M vaccae Ford von Reyn, Dartmouth-Hitchcock Medical Center
	RUTI Luis Ruiz, Archivel
	AdAg85A Zhou Xing, McMaster University
11:30 - 12:00 PM	Q & A for Speakers
12:00 - 01:00 PM	Lunch
01:00 - 03:05 PM	Session V: Partnerships, Communication & Advocacy Co-Chairs: Jelle Thole, TuBerculosis Vaccine Initiative Christine Sizemore, National Institutes of Health
01:00 - 01:30 PM	The Role of EDCTP in Supporting Development Charles Mgone, European and Developing Countries Clinical Trials Partnership
01:35 - 02:05 PM	Partnership Between Diagnostic and Vaccines Rick O'Brien, Foundation for Innovative New Diagnostics
02:10 - 02:20 PM	Stop TB Task Force Presentation Advocacy Issues in TB Vaccine Development Robert Nakibumba, Working Group on New TB Vaccines
02:20 - 03:05 PM	Advocacy Strategies for TB Vaccines Jennifer Woolley, Aeras Global TB Vaccine Foundation Joris Vandeputte, TuBerculosis Vaccine Initiative Robert Nakibumba, Working Group on New TB Vaccines Claire Wingfield, Treatment Action Group
03:05 - 03:30 PM	Coffee/Tea Break
03:30 - 05:00 PM	Meeting for Workshop Chairs Only
03:30 - 05:00 PM	Poster Viewing
05:00 +	Free Evening - A list of local restaurants & activities will be provided
Friday, September 24
08:30 - 10:30 AM	Workshops:
	Session I: Basic Research Chair: Patrick Brennan, Colorado State University
	Session II: Applied Research Chair: Geneviève Inchauspè, Transgene SA
	Session III: Manufacturing, Regulation & Vaccine Access Chair: Jerald Sadoff, Crucell
	Session IV: Clinical Studies on TB Vaccines Chair: Bernard Fourie, Medicine in Need
	Session V: Partnerships, Communication & Advocacy Chair: Christine Sizemore, National Institutes of Health
10:30 - 11:30 AM	Coffee/Tea Break
11:30 - 01:30 PM	Wrap-Up Session - Recommendations from the Working Groups for the TB Vaccine Blueprint Document
01:30 - 02:30 PM	Lunch
02:30 PM	Conference Concluded - A list of local activities will be provided
0:3:00 PM	Optional Tour of Kadroirg Palace & Kumu Art Museum

Off-Site Excursions

Tuesday, September 21, 2010

Old Town Tallinn Medieval Walking Tour - Complimentary with your registration

Duration: Two Hours

Tour Departures: Noon, 1 pm & 2 pm

Please wear your most comfortable shoes!

The tour will depart from and return to Hotel Sokos Viru.

Twisting cobblestone lanes and iron street lamps. Gothic spires and medieval markets. Cappuccino and Wi-Fi. This is the city's famous Old Town. I f you're looking for that mix of historic ambience and cutting-edge culture that defines Tallinn, you'll find it here.

Built up from the 13th to 16th centuries, when Tallinn – or Reval as it was known then – was a thriving member of the Hanseatic trade league, this enclosed neighborhood of colorful, gabled houses, half-hidden courtyards and grandiose churches is, quite rightly, the city's biggest tourist draw. And the fact that it's all neatly packaged within a mostly-intact city wall and dotted with guard towers gives it an extra dose of fairytale charm.

Highlights of the complimentary walking tour include:

Toompea Castle & Tall Hermann’s Tower is one of Estonia's oldest and grandest architectural groupings. The castle is situated on the steep limestone coast, 50 meters above sea level. It is one of the most potent symbols of reigning power, conquered over the centuries by various nations. Today, the Estonian Parliament is housed here.

Alexander Nevsky Cathedral is Tallinn’s largest and grandest cupola cathedral. The large, richly decorated Orthodox church, in mixed historicist style, was built on Toompea Hill in 1900, when Estonia was part of the Russian tsarist empire. The architect of the church was Mikhail Preobrazhenski from St. Petersburg. The church is dedicated to the Prince of Novgorod, Alexander Yaroslavitz Nevsky, who led the famous Ice Battle on the banks of Lake Peipsi on 5 April, 1242 and halted the Germans' eastward advance.

The church’s belltowers hold Tallinn’s most powerful church bell ensemble, consisting of 11 bells, including the largest in Tallinn, weighing 15 tonnes. You can hear the entire bell ensemble playing before church services. The interior, decorated with mosaics and icons, is well worth a visit.

Friday, September 25, 2010

Kadroirg Palace & Kumu Art Museum - $40 per person

Duration: 3.5 Hours

Tour Departure: 3 pm via bus

This tour will include roundtrip bus transportation to and from Hotel Sokos Viru.

Peter I began building Kadroirg Palace in 1718 and it was called Ekaterinenthal, or Catherinenthal, in honor of Catherine I. The architect of the temporary summer residence palace and park was the Italian Niccolo Michetti, who was later involved with the famous Peterhof Palace. It is said that the tsar himself laid the first foundation stones for the palace.

In the 1930s, Kadriorg Palace became a residence for the head of state. On the same level as the palace, across the back flower garden, lies the president’s office building, built a few years before World War II, which today serves as the residence of the President of the Republic of Estonia.

Currently, the baroque Kadriorg Palace is housing the foreign art collection of the Estonian Art Museum, which organizes concerts and theatre performances, lectures and receptions, in addition to art exhibitions.

Opened in 2006, the Kumu is the impressive new main building of the Art Museum of Estonia, and it’s naturally a magnet for every visitor interested Estonian culture. The immense, hightech facility serves as both a national gallery, displaying the classics of Estonian art, and a contemporary art museum, showing off the latest trends. The museum was awarded the 2008 European Museum of the Year.